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The prevalence of type 2 diabetes is rising to epidemic proportions worldwide. Type 2 diabetes is a complex disease caused by dysfunction of multiple organ systems, and disease susceptibility is profoundly influenced by both genetic and environmental factors. It is essential to bring leading professionals in the academic and pharmaceutical communities together with various specialties in diabetes research to share new approaches and research paradigms. The meeting will present the latest discoveries in diabetes research, highlighting essential aspects of diabetes, as well as emerging themes that are likely to provide novel therapeutic approaches. The major topics of the meetings are: Islet Dysfunction; Gut Biology and Systemic Metabolism; CNS Control of Metabolism; Adipocyte Biology; Insulin Resistance; Genetics and Epigenetics; Diabetes and Healthy Lifespan and Regenerative Medicine. The ultimate goal for the meeting is to provide a forum that encourages attendees to communicate and exchange ideas to facilitate an integrative understanding of pathogenesis and development of therapeutic strategies for prevention and treatment of diabetes.