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The 6th Size-Strain conference "Diffraction Analysis of the Microstructure of Materials" (SS-VI) is intended as a continuation of the successful series initiated in 1995 in Liptovsky Mikulas (Slovakia) and continued in 1998 in Freiberg (Germany), 2001 in Trento (Italy), 2004 in Prague as a satellite workshop of the EPDIC9 Conference (Czech Republic) and 2007 in Garmisch-Partenkirchen (Germany). The conference deals with materials microstructure and properties, as they can be studied by diffraction methods, with a special interest in the application of diffraction techniques to polycrystalline materials. In close relation with the previous Size-Strain conferences, SS-VI focuses on methodologies for the study of lattice defects, residual stress and texture in thin films, surfaces and nanostructures, line-broadening analysis, line-profile fitting and modelling based on fundamental parameters for applications in materials science problems. As initiated during SS-V new developments for local measurements such as microbeam diffraction or coherent diffraction are also of special interest.