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The International Conference "Distributed Computing and Grid-technologies in Science and Education" will be held at the Laboratory of Information Technologies (LIT) of the Joint Institute for Nuclear Research (JINR) on 16-21 July 2012. The forthcoming conference will be the fifth one organized by the JINR Laboratory of Information Technologies starting from 2004. The distributed computing and grid-technologies have gone beyond the academic interest since than. The present-day grid-technologies made it possible to integrate the computing centers located at any place worldwide and to provide these computing resources to the users. The present day high technologies ask for the development of high-performance computing. The coverage of the activities involving huge amounts of information throughputs encompasses now not only various areas of natural sciences but also business and industry. During the last few years the implemented distributed computing grid-infrastructure enables the solution of a wide class of tasks that are asking for the processing of enormous amount of data.