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The conference has its roots in two long-standing conference series: Physics and Chemistry of Matrix Isolated Species, started at 1973, and International Conference on Low Temperature Chemistry, started at 1994. Since the last two conferences in Yerevan, Armenia (ICLTC, 2010) and Vancouver, Canada (PCMIS, 2011) it was decided that these two conferences will be combined, and Finland was chosen to host the first new conference. With this new arrangement, the following topics were discussed in the conference: • Quantum Hosts • Molecular Interactions • Low-Temperature Reactions • Spectroscopy and Dynamics • Metal Atoms, Compounds, and Clusters • Atmospheric and Astrochemical Systems • Novel Species and Reactive Intermediates