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University, Shanghai, China Cover Date: 18/ 11 / 2022 Page 1 of 7 BIG BRAIN 2022 Conference for Collaboration in EurAsia Конференция по сотрудничеству в Евразии 2022年亚欧地区合作会议 पवूवू - पाच ाय जीविवानम-्-् 2022 embedding Lomonosov Moscow State University’s BIOKYBERNETIKA БИОКИБЕРНЕТИКА Comprehensive Control for a People-centric Health and Medicine Across EurAsia Organizers Fudan University, Shanghai, People’s Republic of China Shuhua XU School of Life Sciences, Wenhua TIAN School of Public Policy and Social Development Wei LIN Research Institute of Intelligent Complex Systems Lomonosov Moscow State University Faculty of Computational Mathematics and Cybernetics Sergey I. MUKHIN , Sergey V. BOGOMOLOV Heinrich Heine University Düsseldorf, Germany Medical Faculty Jochen MAU Scientific Team Yan LU , Lian DENG , Jing PU School of Life Sciences VIRTUAL CONFERENCE ACROSS SIX EURASIAN TIME ZONES 05-09 December 2022 Fudan On-line Conference 05 - 09 Dec 2022 across EuraAsian Time Zones BIG BRAIN 2022 Structured List of Topics and Authors Date: 22/ 11 / 2022 Page 2 of 7 Scientific Advisor Guoping ZHAO Shanghai Cell Biology Program Committee Ferdinand BINKOFSKI Aachen Clinical Neuroscience Sergey BOGOMOLOV Moscow Stochastic Micro-Macro Modeling Juergen HESCHELER Cologne Stem Cell Research Ljiljana KOLAR-ANIĆ Belgrade Physical Chemistry Wei LIN Shanghai Intelligent Complex Systems Sergey MUKHIN Moscow Multi-Scale Bio-Mathematics Ramakrishnan SWAMINATHAN Chennai Bio-medical Engineering Wenhua TIAN Shanghai Health Service Management Guanyu WANG Shenzhen Mathematical Biology Shuhua XU Shanghai Population Genetics Jianhua ZHANG Oslo Artificial Intelligence Daily Time Frames in December 2022 (only for orientation) China 12:00 14:00 16:00 18:00 20:00 Astana 10:00 12:00 14:00 16:00 18:00 India 09:30 11:30 13:30 15:30 17:30 Samara 08:00 10:00 12:00 14:00 16:00 Moscow 07:00 09:00 11:00 13:00 15:00 Central Europe Winter time 05:00 07:00 09:00 11:00 13:00 Contacts Jing PU e-mail: pujing(at)sinh.ac.cn Sergey MUKHIN e-mail: vmmus(at)cs.msu.ru Jochen Mau e-mail: j.mau(at)hhu.de Fudan On-line Conference 05 - 09 Dec 2022 across EuraAsian Time Zones BIG BRAIN 2022 Structured List of Topics and Authors Date: 22/ 11 / 2022 Page 3 of 7 Structured List of Scientific Talks PART I: THEORIES 1. Stochastic modeling of hierarchical models S. V. Bogomolov (Lomonosov Moscow State University) 2. Simplification of High-dimensional Multi-tempo Dynamic Models E. Shchepakina, V. Sobolev (Samara National Research University), LJ. Zhang (Shandong University of Science and Technology) 3. Allostasis and Allostatic Load: Emerging Paradigms at the Verge between Health and Disease J. W. Dietrich (Ruhr University Bochum) PART II: PERSON’S LIFE-SPHERE Person’s Body Biosphere Cellular System 4. Pluripotent Stem Cells for Basic Research and Regenerative Medicine: What Can We Learn About Embryonic Development? J. Hescheler (University of Cologne) 5. Systems Approach and Control Science Explain the Origin of Aging and its Possible Reversibility A. Khalyavkin (Emanuel Institute of Biochemical Physics of RAS) 6. Mathematical Model of Oscillatory Motion of Chromosomes During Meta- and Anaphase Hedrih (Serbian Academy of Sciences and Arts) 7. Mutations as Activators of Biological Evolution Processes at Genomic and Population Levels A. Sidorova, N. Levashova, A. Garaeva, V. Tverdislov (Lomonosov Moscow State University) 8. Mapping of Cell Membrane Proteome S. Arjunan (Ramaiah University of Applied Sciences, Bangalore, India) 9. Mathematical Model of Cancer Infusion Parabolic System With Nonlocal Diffusion L. Shangerganesh (National Institute of Technology Goa), J. Manimaran (Visvesraya National Institute of Technology) 10. Computational Modeling of Methionine Cycle-based Metabolism and DNA Methylation and the Implication for Anti-cancer Drug Response Jian Li (University Bonn) Physiological Vital Functions Vascular System 11. The Quasi-one-dimensional Model of the Lymph Flow in the Human Lymphatic System. Introduction. A. Mozokhina (Peoples’ Friendship University of Russia), S Mukhin (Lomonosov Moscow State University) 12. Quasi-one-dimensional Mathematical Modeling of Blood Flow in General and Some Applications M. Abakumov. A.Bunicheva, A.Khrulenko, E.Kochetov, V.Kubyshkin, S.Mukhin, K.Mysova, A.Pokladuk, N.Sosnin (Lomonosov Moscow State University) Fudan On-line Conference 05 - 09 Dec 2022 across EuraAsian Time Zones BIG BRAIN 2022 Structured List of Topics and Authors Date: 22/ 11 / 2022 Page 4 of 7 13. Modeling of Building a Neural Network for Diagnosing Blood Flow Disorders Bunicheva A. Y., Kochetov E. V., Mukhin S. I. (Lomonosov Moscow State University) 14. Modeling of Glucose and Insulin Regulation Within the Framework of a Self-consistent Model of the Cardiovascular System A. B. Khrulenko, S. I. Mukhin, K. M. Mysova, A. Yu. Pokladyuk (Lomonosov Moscow State University) Hormone System 15. An Integrate-and-Fire Mechanism for Modeling Rhythmicity in the Neuroendocrine System N. Churilov (St. Petersburg State University), J. Milton (The Clarendon Colleges) 16. Systems Endocrinology: Perspectives of Precision Medicine Based on Physiological Evidence J.W. Dietrich (Ruhr University Bochum) 17. Kinetic Network Modelling of the Hypothalamic-Pituitary-Adrenal (HPA) Dynamics Lj. Kolar-Anić, Ž. Čupić, A. Stanojević, S. Maćešić, M. Andjelković (University of Belgrade), V. Vukojević (Karolinska Institutet) 18. Physicochemical Aspects of Rhythmicity in Neuroendocrine Systems Ž. Čupić (University of Belgrade), V. Vukojević (Karolinska Institutet), Lj. Kolar-Anić (University of Belgrade) Immune System 19. Mathematical Modelling of Respiratory Viral Diseases V. Volpert (Peoples’ Friendship University of Russia ; Université de Lyon) Physical Productivity Functions Motor Brain Functions 20. Dynamic Excitatory-Inhibitary Homeostasis and Energy Supply in the Primary Motor Cortex H. J. Patel, CH. Choi, F. Binkofski (RWTH Aachen University; Research Center Juelich GmbH) Operational Cognitive Functions Sensory System 21. A Geometric Approach to Visual Perception - An Overview V.N. Kozlov (Lomonosov Moscow State University) Mental Workload 22. EEG-based Prediction of Operator Functional State Using Evolutionary Fuzzy Rule-based Models J. Zhang (Oslo Metropolitain University) 23. Cross-task Cognitive Workload Recognition Based on Spatial-Frequency Feature Abstractions of the EEG Signals Z. Yin (University of Shanghai for Science and Technology) Emotions 24. Emotion Recognition in Highly Source-localized EEG Signals Using Motif Patterns with Imbalanced Data N. Ganapathy, H. Kumar, R. Swaminathan (Indian Institute of Technology Madras) Fudan On-line Conference 05 - 09 Dec 2022 across EuraAsian Time Zones BIG BRAIN 2022 Structured List of Topics and Authors Date: 22/ 11 / 2022 Page 5 of 7 25. EEG based Emotion Recognition Using Entropy Features and Bayesian Optimized Random Forest H. Kumar, N. Ganapathy, R. Swaminathan (Indian Institute of Technology Madras) Cognitive Impairment 26. Investigations on the Brain Sub-anatomic Patterns for Early Diagnosis of Mild Cognitive Impairment R. Palanisamy, R. Swaminathan (Indian Institute of Technology Madras) Person’s Eco-Sphere Exposures Living-nature Cohabitation 27. Soil and Human Health: A Review of Modeling Approaches N. Vasilyeva (Dokuchaev Soil Science Institute) 28. Epidemic Basic Ratio Index and Ways to Evaluate It Andrey N. Gerasimov (Sechenov University) 29. On Control of Major Outbreaks of SARS-CoV-2 in China 2020 and 2022 J. Mau (Heinrich Heine University Duesseldorf), WH. Tian (Fudan University) Person’s Socio-Sphere Exposures Population Genetic Factors 30. The Impact of Genetic Admixture on Human Diversity in Asia SH Xu (Fudan University) Social Embedding with Societal Framing Factors Health Systems Context 31. Healthcare Systems in Transition - the Challenge of Complexity and Dynamics R. Sibbel (Frankfurt School of Finance & Management) 32. An Overview of the Health Care System in Kazakhstan from an Individual’s Perspective Nurgozhaev (Med Invest First Ltd. Health Care Consulting, Astana) 33. Health System in Shanghai, a Municipality Directly Under Central Government, China WH Tian (Fudan University) PART III: TECHNOLOGIES AND METHODOLOGIES Engineering 34. Slow/Fast Dynamic Models with Applications to Engineering Problems S. Sazhin (University of Brighton), E. Shchepakina, V. Sobolev (Samara National Research University) Biomedical Engineering 35. Comparative Efficiency of the Physical Sensory Principles in Microbiological Express- Analysis T.M. Zimina, N.O. Sitkov (St. Petersburg Electrotechnical University “LETI“), L.A. Kraeva (Petersburg Fudan On-line Conference 05 - 09 Dec 2022 across EuraAsian Time Zones BIG BRAIN 2022 Structured List of Topics and Authors Date: 22/ 11 / 2022 Page 6 of 7 Institute of Epidemiology and Microbiology), V.E. Lemozerskii (St. Petersburg Electrotechnical University “LETI“), A. F. Kostko (ITMO University) Information Sciences Computing Methods 36. On the Method of Graph-Based Design Languages S. Vogel (Hochschule Ravensburg-Weingarten University of Applied Sciences), S. Rudolph (University of Stuttgart) 37. Practical Features of Coronary Flow Simulations for the Patients Undergoing Percutaneous Coronary Intervention S. Simakov (Moscow Institute of Physics and Technology), T. Gamilov (Sechenov University), A.Danilov (Marchuk Institute of Numerical Mathematics RAS), A. Rebrova (Moscow Institute of Physics and Technology), Fuyou Liang (Shanghai Jiao Tong University) 38. The Direct and Inverse MEG Problem Zakharova T.V., Pakhnenko I.P., Sabirov A.I. (Lomonosov Moscow State University) Cellular Level Methods 39. Chiral Correspondences in Pharmacology E. Semenova, E. Belova, V. Tverdislov (Lomonosov Moscow State University) 40. Model of 3-dimensional α-Helix Structure Formation Based on Two-particle Model in Lennard-Jones Potential N. Levashova, A. Sidorova, K. Zuev, V. Tverdislov (Lomonosov Moscow State University) 41. Localization of Secondary Structures in Proteins of Various Functional Classes O. Bagrova, E. Belova, V. Tverdislov (Lomonosov Moscow State University) 42. Assessment of the Chirality of Regular and Irregular Protein Structures. Application in Bioengineering A. Lutsenko, A. Sidorova, D. Shpigun, D.Lukyanenko (Lomonosov Moscow State University) 43. Characterization of Fast Dynamical Processes in Live Cells via Massively Parallel Fluorescence Correlation Spectroscopy Integrated With Fluorescence Lifetime Imaging Microscopy (mpFCS/ FLIM) S. Oasa Karolinska Institutet), A.J. Krmpot, S.N. Nikolić (University of Belgrade), L. Terenius, R. Rigler, V. Vukojević (Karolinska Institutet) Decision Support 44. Direct Numerical Modeling and Convolutional Neural Networks for Medical Ultrasound Problems I. Petrov, A. Vasyukov (Moscow Institute of Physics and Technology) 45. Optimal Strategies for Two-stage Combined Treatment of Blood Cancer N.L. Grigorenko, E.N. Khailov, E.V. Grigorieva, A.D. Klimenkova (Lomonosov Moscow State University) Data-Analytic Sciences 46. Estimation of Adjusted Relative Risks in Log-binomial Regression S. Wagenpfeil, J. Schöpe, A. Bekhit (Saarland University) Fudan On-line Conference 05 - 09 Dec 2022 across EuraAsian Time Zones BIG BRAIN 2022 Structured List of Topics and Authors Date: 22/ 11 / 2022 Page 7 of 7 47. Assessing the Bioequivalence of Different Drugs Dranitsyna M., Klimenko V., Panov P., Zakharova T. (RUDN ; Lomonosov Moscow State University) PART IV: FUTURE RESEARCH AND HEALTH POLICY DESIGN Control of Internal Dynamics of Physiological Processes 48. Disorders of Multi-scale Control GY. Wang (Chinese University of Hong Kong) 49. Axiomatic Functional Biodynamics J. Mau (Heinrich Heine University Düsseldorf) Control of External Dynamics in Local Conditions 50. From Theory to Transcontinental Validation – a BIG BRAIN Research Agenda J. Mau (Heinrich Heine University Düsseldorf)