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International Conference "INPEC-2014" was 21st Conference organized by International Network of Protein Engineering Centers (INPEC. The Conference took place in Gelios Hotel, Zelenogorsk, St.Petersburg region in September 10-14, 2014. The Conference was devoted to last achievements in protein engineering and there were participants from USA, Canada, Brasil, Germany, Denmark, Israel, France, India, South Korea and Russian Federation