ИСТИНА

Cell-wall glycopolymers of Gram-positive bacteria are covalently linked to peptidoglycan. They have a number of important physiological functions and are involved in the cell communication within the microbial community and the environment. The cell walls of two strains of Promicromonospora citrea, VKM Aс-665T and VKM Ac-1028, from the phylum Actinobacteria (A4α peptidoglycan type, lack aerial mycelium) were found to include non-phosphorylated anionic glycopolymers. They bear pyruvic acid acetals (of R-configuration), which define or enhance their negative charge. The cell wall of P. citrea Aс-665T contains two glycopolymers of the sort, including pyruvylated galactan 1 and Kdn-teichulosonic acid 2. The cell wall of P. citrea Aс-1028 contains a pyruvylated teichuronic acid 3. These glycopolymer structures are reported for the first time in nature. They expand the notion on the diversity of the organic world and biosynthetic potential of microorganisms.