ИСТИНА

Research center of neurology Purpose: To report the result of retrospective analysis of frequency of postprocedural ischemic silent brain lesion occurrence on MRI DWI after CAS. Methods and material: From August 2016 to December 2017, 42 patients (Men = 32, Women – 10; median age 72 years) underwent Casper stent implantation for carotid artery stenosis. Indications for digital subtraction angiography included stenosis >70% of vessel diameter by ultrasound examination of the proximal internal carotid artery in symptomatic patients or asymptomatic patients. Casper stent was used in case of symptomatic and asymptomatic patients with several and/or “dangerous” carotid artery stenosis on fluoroscopy by operator opinion. For all patients, a distal protection device was used. Within 24 hours after procedure MRI DWI examination was performed and acute silent ischemic brain lesion was estimated. The results were compared with previously received data on common carotid stent. Result: Stent deployment was completed successfully in all cases with 100% technical success. There were no adverse neurological events or mortalities in early postprocedure period. The frequency of occurrence of silent ischemic brain lesion was significantly low. (p<0.05) Conclusion: The Casper carotid stent demonstrated safety and efficacy in the treatment of carotid stenosis. Its double layer structure seems to block microembolus and impact occurrence of ischemic silent brain lesions.