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The geomechanical approach to modeling deformation and seepage is presented. Three stages of modeling are described: choosing the appropriate mechanical model and its adapting to the case in question, experimental determination of the parameters of the model, simulation of processes of seepage for particular configurations of the well. The used model allows describing the main peculiarities of the mechanical behavior of the collector: influence of pore pressure on deformation; influence of not only shear but also comprehensive stress and pore pressure on transition to inelastic behavior; appearance of inelastic volumetric deformation and its non-trivial dependence on the stress state; anisotropy of elastic, strength and seepage properties; non-obvious dependence of permeability on stress-strain state. The model unites the essential features of Hill’s plastic flow theory for anisotropic materials and Drucker-Prager theory for inelastic deformation of soils. The results of experimental determination of the involved parameters for the the reservoir of Filanovskii oil and gas condensate field obtained using true triaxial loading system are presented.