|
ИСТИНА |
Войти в систему Регистрация |
ФНКЦ РР |
||
Downregulation of ACh secretion in reinnervated mouse neuromuscular junctions involving PKC activity and Voltage-dependent K+-channelsдоклад на конференции
- Авторы: Балезина О.П., Богачева П.О.
- Международная Конференция : Meeting of the Physiological Society "Physiology 2009"
- Даты проведения конференции: 2009
- Тип доклада: не указан
- Докладчик: не указан
- Место проведения: Dublin, Ireland, Ireland
-
Аннотация доклада:
In previous studies we have shown that Ca2+ entering the terminal through L-type Ca2+-channels triggers the release of intracellular Ca2+ from ryanodine stores, which in turn leads to depression of ACh release in reinnervated mouse neuromuscular junctions. Ca2+-dependent protein kinase C which is known (along with other substrates) to modulate the activity of voltage-dependent K+-channels (Kv) was considered as a possible target for this Ca2+ signal.
- Добавил в систему: Богачева Полина Олеговна