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I report the results of our multiwavelength investigations of morphology, kinematics and evolution of star formation regions in several nearby irregular galaxies, which are the perfect laboratories for studying of the ISM regulated by stellar feedback. Our deep H-alpha images of selected galaxies obtained with Russian 6-m BTA telescope reveal not only bright HII regions, but also a lot of faint ionized bubbles and filament-like structures associated with ongoing star formation. We have studied the emission spectrum, kinematics and ionization conditions of these structures and compared it with the available information about young stellar population and neutral gas morphology and kinematics. Inside the supergiant HI superbubbles of two galaxies we have detected faint kpc-sized H-alpha shells, which most probably were formed by the influence of Lyman radiation escaped from the bright HII regions in these galaxies. In addition I will briefly discuss our findings on the role of the hard UV radiation in the dust composition of ISM.