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We report constraints on anomalous tWb couplings which parameterize the contribution of New Physics in weak tWb interactions. We compared indirect constraints obtained from B-physics (from B → Xsγ, B → Xsl+l−, B-B ̄oscillations) and direct constraints from the t-channel single top quark production. We show that in the case of two-dimensional scenarios when two couplings are nonzero, the combination of the constraints of both types are in agreement with each other and it is possible to narrow down the allowed areas. So far we found no deviations fromthe Standard Model are seen.