ИСТИНА

More than a decade our group deals with the chemistry of N-heterocyclic carbenes bearing expanded, six-, seven- or eight-membered ring, er-NHCs. For such carbenes, it is possible to vary the stereoelectronic properties in a wider range than for their five-membered ring counterparts. We have developed approaches for synthesis and isolation of carbenes and their late transition metal complexes (Cu, Ag, Au, Pd, Pt). Superior stereoelectronic properties of er-NHCs enabled us to develop highly efficient catalytic systems for important organic transformations such as C-C and C-N cross-coupling, addition of nucleophiles to acetylenes, CuAAC, CH borylation. In many cases the developed synthetic protocols are not only efficient, but also meet the requirements of green chemistry: water as solvent, solvent-free conditions, environmentally benign and affordable co-catalysts, and additives.