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Particle detection by a system of the double-sided microstrip silicon detectors arranged in a telescope (STT1) provides information on a particle track, on time of its detection, identification of its type and measurement of its energy losses in sensitive layers of the detectors. The developed STT calibration method uses all this information that allows approach to a precision of an initial kinetic energy reconstruction at level of 1% for the products of nuclear reactions such as protons and deuterons in a dynamic range of 3 to 50 MeV (up to 70 MeV with accuracy losses). The described method is branched procedure which includes the integrated comparative analysis of response of all read-out channels. Modeling is a significant part of the development. The method uses data from laboratory commissioning measurements (test-pulse calibration of electronics and detection of radiation from α-sources) as well as from measurements of a scientific experiment. Combination of this method with a method of a track reconstruction allows defining an initial particle momentum that is necessary for perspective studies, some of them require to reconstruct an excitation energy of a pair of protons with an accuracy of 0.1-0.3 MeV in range of 1-40 MeV.