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Seasonality of lipid levels as well as of other cardio-vascular risk factors which was established in several studies could contribute to the seasonal variation of cardio-vascular morbidity and mortality. Also it is well known that anti-atherogenic high density lipoproteins (HDL) has anti-inflammatory and immunodulatory properties. The purpose of this study was to find the relations of adaptive and innate immune cells count with seasonal HDL levels.