Аннотация:Surfactants as components of cosmetic products contact the human organism inevitably. One of important factors of human immune system is lysozyme, which is an enzyme with bacteriolytic activity. In the following work, influence of sodium dodecyl sulfate (anionic surfactant, which is present in most washing remedies) on the activity of lysozyme is investigated. Lysozyme is inhibited by sodium dodecyl sulfate, and its activity decreases by half in presence of 0,29 mM sodium dodecyl sulfate, what is more than 1000 times lower than a permitted concentration of this surfactant in cosmetics. This result shows the necessity of revision for permitted concentration of sodium dodecyl sulfate.