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Disorders in the Morphology and Nanostructure of Erythrocyte Membranes after Long-term Storage of Erythrocyte Suspension: Atomic Force Microscopy Studyстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 9 декабря 2015 г.
- Авторы: Moroz VV, Chernysh AM, Kozlova EK, Sergunova VA, Gudkova OE, Khoroshilov SE, Onufrievich AD, Kostin AI
- Журнал: Bulletin of Experimental Biology and Medicine
- Том: 159
- Номер: 3
- Год издания: 2015
- Издательство: Springer Nature
- Местоположение издательства: Switzerland
- Первая страница: 406
- Последняя страница: 410
- DOI: 10.1007/s10517-015-2975-9
- Аннотация: Disorders in the erythrocyte morphology and structure of their membranes during long-term storage of erythrocyte suspension (30 days at 4°C) were studied by atomic force microscopy. The morphology and nanostructure of erythrocyte membranes, biochemical parameters, ion exchange parameters, and hemoglobin spectra were recorded. The transformation of erythrocyte morphology and destruction of their membranes were observed throughout the storage period. Irreversible forms of spheroechinocytes and their fragments formed by the end of storage. The concentrations of potassium ions and lactate in solution of the blood preservatiive increased, while pH value decreased. Hemolysis detected by the erythrocyte "leakage" effect was observed starting from days 16-23 of storage.
- Добавил в систему: Козлова Елена Карловна