Аннотация:Bacteriolytic activity of human interleukin-2 was studied with various microorganisms, namely Escherichia coli, Bifidobacterium bifidum, Lactobacillus plantarum etc. Experiments were carried out at different values of pH, ionic strength, concentration of surfactant. In particular, bacteriolytic activity of interleukin-2 was investigated in the presence of sodium dodecyl sulfate (SDS), which is a part of a number of medications. It was found that 1 mg/ml of SDS had no effect on bacteriolytic properties of interleukin-2. Sodium dodecyl sulfate at the same concentrations itself in the absence of interleukin-2 did not influence on bacteria lysis.
This work was supported by Russian Science Foundation, grant 15-14-00012.