3-D Mouse Brain Model Reconstruction from a Sequence of 2-D Slices in Application to Allen Brain Atlas

Авторы: Osokin Anton, Vetrov Dmitry, Kropotov Dmitry
Сборник: Computational Intelligence Methods for Bioinformatics and Biostatistics
Серия: Lecture Notes in Computer Science
Том: 6160
Год издания: 2010
Издательство: SPRINGER-VERLAG BERLIN
Местоположение издательства: HEIDELBERGER PLATZ 3, BERLIN, GERMANY,D-14197
Первая страница: 291
Последняя страница: 303
DOI: 10.1007/978-3-642-14571-1_22
Аннотация: The paper describes a method of fully automatic 3D-reconstruction of a mouse brain from a sequence of histological coronal 2D slices. The model is constructed via non-linear transformations between the neighboring slices and further morphing. We also use rigid-body transforms in the preprocessing stage to align the slices. Afterwards, the obtained 3D-model is used to generate virtual 2D-images of the brain in arbitrary section-plane. We use this approach to construct a high-resolution anatomic 3D-model of a mouse brain using well-known Allen Brain Atlas which is publicly available.
Добавил в систему: Осокин Антон Александрович

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