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Increases in microvascular perfusion and tissue oxygenation via pulsed electromagnetic fields in the healthy rat brainстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 26 апреля 2019 г.
- Авторы: Bragin Denis E., Statom Gloria L., Hagberg Sean, Nemoto Edwin M.
- Журнал: Journal of Neurosurgery
- Том: 122
- Номер: 5
- Год издания: 2015
- Издательство: American Association of Neurological Surgeons
- Местоположение издательства: United States
- Первая страница: 1239
- Последняя страница: 1247
- DOI: 10.3171/2014.8.JNS132083
- Аннотация: High-frequency pulsed electromagnetic field stimulation is an emerging noninvasive therapy being used clinically to facilitate bone and cutaneous wound healing. Although the mechanisms of action of pulsed electromagnetic fields (PEMF) are unknown, some studies suggest that its effects are mediated by increased nitric oxide (NO), a well-known vasodilator. The authors hypothesized that in the brain, PEMF increase NO, which induces vasodilation, enhances microvascular perfusion and tissue oxygenation, and may be a useful adjunct therapy in stroke and traumatic brain injury. To test this hypothesis, they studied the effect of PEMF on a healthy rat brain with and without NO synthase (NOS) inhibition.
- Добавил в систему: Брагин Денис Евгеньевич