Chromatographic analysis of Passifit multicomponent pharmaceutical syrupстатья
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Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
Аннотация:Procedures are developed for the qualitative analysis of a new pharmaceutical preparation, Passifit syrup. The conditions for the separation of the active substances were optimized. Valerian and hop extracts were detected by thin-layer chromatography on Kieselgel 60/Kieselguhr F-254 plates. Menthol (the volatile component of peppermint oil), thymol and its isomer carvacrol (the components of thyme extract), and sorbic acid (preserving agent) were identified by gas-liquid chromatography on a capillary column with an OV-101 stationary phase and a flame-ionization detector. Luteolin, thymol, rutin, and sorbic acid were identified by reversed-phase HPLC on a Zorbax SB C18 column in a gradient elution mode with UV detection at 210 and 330 nm. Rutin was not detected among the components of the syrup.