Enzymes for Detoxification of Various Mycotoxins: Origins and Mechanisms of Catalytic Action

Lyagin, I.; Efremenko, E.

Информация о цитировании статьи получена из Web of Science, Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 15 августа 2019 г.

Авторы: Lyagin I., Efremenko E.
Журнал: Molecules
Том: 24
Номер: 13
Год издания: 2019
Издательство: MDPI
Местоположение издательства: Basel, Switzerland
Первая страница: 2362
DOI: 10.3390/molecules24132362
Аннотация: Mycotoxins are highly dangerous natural compounds produced by various fungi. Enzymatic transformation seems to be the most promising method for detoxification of mycotoxins. This review summarizes current information on enzymes of different classes to convert various mycotoxins. An in-depth analysis of 11 key enzyme mechanisms towards dozens of major mycotoxins was realized. Additionally, molecular docking of mycotoxins to enzymes’ active centers was carried out to clarify some of these catalytic mechanisms. Analyzing protein homologues from various organisms (plants, animals, fungi, and bacteria), the prevalence and availability of natural sources of active biocatalysts with a high practical potential is discussed. The importance of multifunctional enzyme combinations for detoxification of mycotoxins is posed.
Добавил в систему: Лягин Илья Владимирович

	ИСТИНА	Войти в систему Регистрация
	ФНКЦ РР
	Главная Поиск Статистика О проекте Помощь

ИСТИНА

ФНКЦ РР

Enzymes for Detoxification of Various Mycotoxins: Origins and Mechanisms of Catalytic Actionстатья Исследовательская статья

Прикрепленные файлы