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What Oscillatory Activity in Simple Nervous Systems Can Tell Us about Human Brain Rhythms: Pacemaker Frequency-Generators in the Ganglions of Grape Snail?статья Тезисы
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 8 февраля 2017 г.
- Авторы: Danilova Nina N., Khludova Ludmila K., Chernorizov Alexander M.
- Журнал: International Journal of Psychophysiology
- Том: 108
- Год издания: 2016
- Издательство: Elsevier BV
- Местоположение издательства: Netherlands
- Первая страница: 67
- Последняя страница: 67
- DOI: 10.1016/j.ijpsycho.2016.07.221
- Аннотация: Background: Mechanisms and functions of oscillatory activity in human brain remains one of the mysterious puzzle in cognitive psychophysiology. Brain oscillations are shown to be closely associated with mental functions from perception to consciousness. All that determines ever-increasing interest of scientists to evolution of biological rhythms. The oldest evolutionary mechanisms for generation of rhythmic activity are the pacemaker neurons located in different nervous structures (Grechenko, 2008). In this connection, it is of great interest to study the pacemaker activity in animals with simple nervous system. Methods and Results: In experiments on semi-intact preparation of a grape snail the spontaneous local summary oscillatory activity from different ganglions was registered using glass macroelectrodes. To estimate the spectral composition of the oscillations we used the fast Fourier transform for the construction periodograms after digitizing the source data on 3 s intervals (Shumway, Stoffer 2011). The parameters of oscillations were identified and analyzed using auto-correlation, cross-correlation and wavelet analysis. Rhythmic activity looked like a recurring spindles, which are typical of pacemaker activity. The amplitude of the oscillations ranged between 20 to 35 mkV. It was found that each ganglion is characterized by its own stable frequency of pacemaker activity: for parietal ganglia these oscillatory frequencies were varied in the range of 0.2 – 55 Hz, for abdominal ganglion – in the range of 0.5 - 7 Hz, for the pleural ganglia – in the range of 20 - 40 Hz. Discussion: Frequency ranges of oscillatory activity in snail with simple nervous system is very close to the oscillation frequency characteristics revealed in simplest organisms (bacteria, sponges, yeast) and vertebrates (Grechenko et al. 2016): 1. Frequencies of pacemaker activity in snail vary in a wide range of frequencies, corresponding delta-, teta-, alpha-, beta- and gamma-rhythms in high vertebrates, including human. 2. Different frequency generators located in different parts of the nervous system (ganglia) that perform different functions. Conclusion: The neuronal pacemaker activity of mollusk and other invertebrates may be used as an experimental model to shed light on evolutionarily ancient functions and molecular mechanisms of oscillatory activity in the human brain.
- Добавил в систему: Данилова Нина Николаевна