3D genomics imposes evolution of the domain model of eukaryotic genome organizationстатья
Статья опубликована в высокорейтинговом журнале
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Дата последнего поиска статьи во внешних источниках: 18 июля 2016 г.
Аннотация:The hypothesis that the genome is composed of a
patchwork of structural and functional domains (units) that
may be either active or repressed was proposed almost
30 years ago. Here, we examine the evolution of the domain
model of eukaryotic genome organization in view of the expansion
of genome-scale techniques in the twenty-first century
that have provided us with a wealth of information on
genome organization, folding, and functioning.