Аннотация:Apoptosis in cardiomyocytes was induced by incubation of shards of cardiac tissues under condition of anoxia. We have studied dynamic of ultrastructure during apoptosis. Electron-microscopic investigation discovered (previously unknown) changes in mitochondrial ultrastructure. Effect of BHT on mitochondrial ultrastructure during apoptosis was investigated. Results of our study are discuss in connection with conception of changes in mitochondrial reticulum ultrastructure during apoptosis.