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Effect of chemical mutagens on spermatogenesis in mammals. Cytogenetic analysisстатья
Дата последнего поиска статьи во внешних источниках: 28 мая 2015 г.
- Авторы: Zakhidov S.T., Paranyushkina L.P., Mahran Hoda A.H, El-Saed Kasem Abdel-Hadi, Golichenkov V.A.
- Журнал: Biology Bulletin
- Том: 21
- Номер: 3
- Год издания: 1994
- Издательство: M A I K Nauka - Interperiodica
- Местоположение издательства: Russian Federation
- Первая страница: 267
- Последняя страница: 274
- Аннотация: It was shown using the micronucleus test and estimating the defects of sperm heads that premeiotic and meiotic mammalian cells are genetically very sensitive to dipin and nitrosomethylurea. In rats, unlike mice, the stem and differentiating spermatogonia with serious chromosomal defects are not eliminated and pass through a "sieve" of mitotic and meiotic divisions reaching the stage of round spermatids. Our observation suggest long-term preservation dipin-induced, rather than nitrosomethylurea-induced, mutation in the stem cells of both mice and rats
- Добавил в систему: Захидов Сабир Тишаевич