Tricyclic derivatives of bispidine as AMPA receptor allosteric modulatorsстатья
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Дата последнего поиска статьи во внешних источниках: 15 апреля 2020 г.
Аннотация:Four new tricyclic derivatives of 3,7-diazabicyclo[3.3.1]-
nonane (bispidine) have been synthesized. In vitro patch
clamp investigation has revealed for one of them the positive
modulation of the kainate-induced AMPA receptor currents
in a nanomolar concentration range, and for two other
compounds the corresponding negative modulation has been
demonstrated.