The Road to Optogenetics: Microbial Rhodopsins 2016, Vol. 81, No. 9, pp. 928-940статья
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Дата последнего поиска статьи во внешних источниках: 27 ноября 2016 г.
Аннотация:Optogenetics technology (using lightsensitive microbial proteins to control animal cell physiology) is becoming
increasingly popular in laboratories around the world. Among these proteins, particularly important are rhodopsins that
transport ions across the membrane and are used in optogenetics to regulate membrane potential by light, mostly in neu
rons. Although rhodopsin ion pumps transport only one charge per captured photon, channelrhodopsins are capable of
more efficient passive transport. In this review, we follow the history of channelrhodopsin discovery in flagellate algae and
discuss the latest addition to the channelrhodopsin family, channels with anion, rather than cation, selectivity.