Search for association between C/T polymorphism of AMPD1 gene and sports achievement in sambo wrestlingстатья
Статья опубликована в журнале из списка RSCI Web of Science
Статья опубликована в журнале из перечня ВАК
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 8 февраля 2017 г.
Аннотация:Abstract. The study is devoted to C34T polymorphism of adenosine monophosphate deaminase 1 (myoadenylate deaminase) or AMPD 1 gene associated with physical efficiency in humans. Various groups of athletes were observed to assess the influence of this marker on success and selection in sports. 318 ethnic Russian males between 18 and 30 years of age participated in the research. 92 of them represented the reference group which was not involved in sport and 226 sambo wrestlers. Samples of buccal epithelium were taken from athletes at the Russian Sambo championship of 2008 (Moscow). As a whole, the examined group of sambo wrestlers showed some decrease in the occurrence of T allele and TT genotype, thus indicating some advantage of carriers of primary C allele associated with the normal level of activity of the AMPD1 enzyme. At the same time, no statistically significant differences in the frequencies of AMPD1 genotypes and alleles with the increase of sports qualification (KMS, MS, MSMC, and MMS) were discovered.