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Identifying the role of cytochrome c in post-resuscitation pathophysiologyстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Дата последнего поиска статьи во внешних источниках: 15 апреля 2020 г.
- Авторы: Chalkias Athanasios, Kuzovlev Artem, Noto Antonio, d'Aloja Ernesto, Xanthos Theodoros
- Журнал: The American journal of emergency medicine
- Том: 33
- Номер: 12
- Год издания: 2015
- Первая страница: 1826
- Последняя страница: 1830
- DOI: 10.1016/j.ajem.2015.09.006
- Аннотация: Cytochrome c, an electron carrier that normally resides in the mitochondrial intermembrane space, may translocate to the cytosol under ischemic and hypoxic conditions and contribute to mitochondrial permeability transition pore opening. In addition, reperfusion of brain tissue following ischemia initiates a cell death cascade that includes cytochrome c-mediated induction of apoptosis. Further studies are needed to determine the contribution of cytochrome c in the regulation of cell death, as well as its value as an in vivo prognostic marker after cardiac arrest and resuscitation.
- Добавил в систему: Кузовлев Артем Николаевич