Non-compliance in female patients with functional constipation has link to psychoemotional disorders but not to severity of somatic symptoms

Morozova, M.; Ulyanin, A.; Poluektova, E.; Ivashkin, V.; Shifrin, O.; Alekseev, A.; Rupchev, G.; Beniashvilli

Авторы: Morozova M., Ulyanin A., Poluektova E., Ivashkin V., Shifrin O., Alekseev A., Rupchev G., Beniashvilli
Журнал: European Psychiatry
Том: 63
Номер: S
Год издания: 2020
Издательство: Cambridge University Press
Местоположение издательства: United Kingdom
Первая страница: 62
Последняя страница: 62
Номер статьи: EPP0090
DOI: 10.1192/j.eurpsy.2020.5
Аннотация: Prevalence of functional constipation (FC) among adults worldwide is about 24%. The disease affects female more than male. Сomorbid psycho-emotional disorders, i.e. anxiety and depression might be associated with FC but the role of somatization and distress in such patients is still unclear. Actual schemes of symptomatic treatment of FC have low efficiency. At the same time only 50% of patients with FC follow the doctor’s recommendations. Difficulty of identification of non-compliant patients can have impact on the treatment outcome. To assess adherence to treatment in females with FC (ROME IV). 40 females with FC (ROME IV) were examined for somatic symptoms and tested by Latent Dysphoric Scale (LDS) and the Four-Dimensional Symptom Questionnaire (4DSQ) for emotional disorders. All patients had FC and were prescribed laxatives. Somatization and dysphoria, but not depression and anxiety were presented. Two weeks later patients were examined on their compliance. 14 patients stopped treatment (noncompliant group - NCP) and 26 patients continued treatment (compliant group - CP). No difference in age, years of disease duration and somatic symptoms severity between NCP and CP before the treatment was observed. All NCP and CP showed equal positive response to treatment. The difference concerned only emotional status: latent dysphoria and all symptoms of 4DSQ: distress , somatization, depression and anxiety were more severe in the NCP group (p<0,05 for each index). Emotional disturbances, including latent dysphoria, distress, somatization, anxiety and depression but not severity of somatic symptoms, predispose to non-compliance in female with FC.
Добавил в систему: Рупчев Георгий Евгеньевич

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