Comment on the theory of protein adsorption on a biospecific rigid matrixстатья
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Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
Аннотация:A new model for biospecific sorption of proteins is proposed. The model considers adsorption on a rigid non-swelling matrix, in particular, silica. The quantity of ligand accessible to a protein is estimated using the fractal approach. Steric (not allosteric) interactions between a protein sorbed and a cluster of attached ligands are discussed. It is shown that biospecific binding of a protein decreases as the surface concentration of attached ligands is increased.