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Impact of Modification on the Energy Characteristics of Surfaces and Matrix Properties of the New Effective Polymer Vascular Implantsстатья
Дата последнего поиска статьи во внешних источниках: 12 января 2022 г.
- Авторы: Bogdanova Yu G., Antonova L.V., Silnikov V.N., Khanova M.Yu, Senokosova E.A., Barbarash L.S.
- Журнал: Key Engineering Materials
- Том: 899
- Год издания: 2021
- Издательство: Trans Tech Publications Ltd.
- Местоположение издательства: Germany
- Первая страница: 342
- Последняя страница: 354
- DOI: 10.4028/www.scientific.net/KEM.899.342
- Аннотация: New tissue-engineered vascular prostheses of small diameter (4mm) based on biodegradable polymer backbone – poly(ε-caprolactone) (PCL) and its composition with poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV/ PCL) were created. The full cycle of surface modification of the backbone with polyvinylpyrrolidone and drugs permitted to increase significantly the atrombogenic and antimicrobial properties of prostheses and provide its effective matrix properties. Both types of the developed constructs are suitable for testing in vivo. The energy characteristics of the prosthesis surfaces at the different interfaces were determined. It was established that the value of the energy of the "polymer, saturated with octane/water" interface can be used as a parameter for predicting cell adhesion and proliferation in the case when it is difficult to determine or to distinguish the energy characteristics of the surfaces of tissue-engineered materials at the interface with air.
- Добавил в систему: Богданова Юлия Геннадиевна
Прикрепленные файлы
| № | Имя | Описание | Имя файла | Размер | Добавлен |
|---|---|---|---|---|---|
| 1. | Statya.pdf | Statya.pdf | 730,1 КБ | 26 августа 2021 [yulibogd] |