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Six-Month Quality of Life in COVID-19 Intensive Care Unit Survivors, Journal of Cardiothoracic and Vascular Anesthesiaстатья
- Авторы: Likhvantsev V., Landoni G., Perekhodov S., Chaus N., Kadantseva K., Ermokhina L., Baeva A., Yadgarov M., Berikashvili L., Kuzovlev A., Grechko A.
- Журнал: Journal of Cardiothoracic and Vascular Anesthesia
- Год издания: 2021
- Издательство: W. B. Saunders Co., Ltd.
- Местоположение издательства: United Kingdom
- DOI: 10.1053/j.jvca.2021.08.036
- Аннотация: Objective(s): Since there is increasing evidence of serious deterioration in long-term Quality ofLife (QoL) in COVID-19 intensive care unit (ICU) survivors, we identified predictors of poor quality of life in these patients.Design: Prospective cohort study.Setting: Research hospital repurposed in to a COVID-19 center.Participants: Consecutive patients admitted in COVID-19 ICU between March and June 2020. Interventions: A SF-36 questionnaire, which includes physical and mental items, was used 6 months after patients discharge.Measurements and Main Results: 403 patients were managed in the ICU with a hospital mor- tality of 181/403 (44.9%) while 16 (4.0%) further patients died within 6 months. Among the 125 questionnaire responders, only 32.0% and 52% had a normal quality of life in terms of the physi- cal and mental component of health. Multivariable analysis identified low-molecular-weight heparin treatment in ICU as the only modifiable factor associated with an increase in physical component of QoL OR: 3.341 (95%CI 1.298-8.599), p=0.012, while age >52 years OR 0.223 and female sex OR 0.321 were significantly associated with a decrease in the physical compo- nent. Medical history of cerebrovascular insufficiency was significantly associated with a de- crease in mental component of QoL OR: 0.125, while the only factor associated with an increase in the mental health component was BMI ≥ 27.6 kg / m2 OR 7.466.Conclusions: In COVID-19 intensive care unit survivors we identified treatment with low mo- lecular weight heparin as a predictor of improved physical component of QoL at 6-months.
- Добавил в систему: Ядгаров Михаил Яковлевич