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CHANGES IN THE LIPID PEROXIDATION-ANTIOXIDANT PROTECTION SYSTEM IN WOMEN WITH OVARIAN HYPERANDROGENISM AT DIFFERENT PERIODS OF REPRODUCTIVE AGE С. .статья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 15 сентября 2021 г.
- Авторы: Kolesnikova L.I., Krusko O.V., Belenkaya L.V., Sholokhov L.F., Grebenkina L.A., Kurashova N.A., Kolesnikov S.I.
- Журнал: Bulletin of Experimental Biology and Medicine
- Том: 170
- Номер: 3
- Год издания: 2021
- Издательство: Springer Nature
- Местоположение издательства: Switzerland
- Первая страница: 308
- Последняя страница: 311
- DOI: 10.1007/s10517-021-05057-y
- Аннотация: We studied changes in LPO processes and antioxidant protection system in women with ovarian hyperandrogenism at various periods of reproductive age 18-45 years. An age-related decrease in total antioxidant activity and accumulation of secondary LPO products, ketodiens and coupled trienes, were found; these changes were accompanied by an increase in the level of superoxide dismutase and a decrease in the concentrations of reduced glutathione, α-tocopherol, and retinol. Women of early reproductive age (18-35 years) with hyperandrogenism were characterized by increased content of oxidized glutathione accompanied by a decrease in the level of α-tocopherol and retinol in comparison with the control group. In women of late reproductive age (35-45 years) with hyperandrogenism, increased superoxide dismutase activity in comparison with the control group was revealed.
- Добавил в систему: Колесников Сергей Иванович