Аннотация:The article presents an assessment of the relationship between the average annual values of outbreaks of major infectious diseases in the world (ODW) with the UV Index, the radio emission flux of 2800 MHz (F10.7 cm) and the values of the average magnetic field of theSun (MF) for the period from 2008 to 2019 (24 solar activity cycle). Data on the number ofoutbreaks of diseases were selected on the World Health Organization website as a cumulative value of outbreaks of Ebola virus, AH7N9, MERS-CoV, A(H1N1), etc. It was found thatthe peak of disease outbreaks corresponds to the year of maximum 24 cycles of solar activity(2014). The correlation of the average annual values of the number of epidemics with the indicators of solar factors was: r~ -0.6 (ODW/UVI), r~0.53 (ODW/F10.7cm).and r~0.88(ODW/MF). It is concluded that the dynamics of disease outbreaks is related to UV Index,which is due to the intensity of the UVB range (280–315 nm), correlating with a change in the2800 MHz radio emission flux in the NUV295–305 nm subband, as well as with a change inMF in NUV305–315 nm. The role of the erythemic border of UVB (λ315 nm) is noted