Stress-Protective and Cross Action of the Extracellular Reactivating Factor of the Microorganisms of the Domains Bacteria, Archaea, and Eukaryotaстатья
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Дата последнего поиска статьи во внешних источниках: 25 декабря 2013 г.
Аннотация:Abstract—Cross protection of members of the domains Bacteria, Archaea, and lower Eukaryota from stress
factors due to the action of extracellular lowwmolecular metabolites with adaptogenic functions was shown.
The adaptogen produced by Luteococcus japonicus subsp. casei and described previously as a reactivating facc
tor (RF) was shown to protect the yeasts Saccharomyces cerevisiae, archaea Haloarcula marismorti, and the
cells of higher eukaryotes (HeLa) against weak stressor impacts. Production of an archaeal extracellular
metabolite with a weak adaptogenic effect of the producer cells and capable of a threefold increase in survival
of heattinactivated yeast cells was discovered. Our results confirm the similarity of the compensatory adaptive
reactions in prokaryotes (bacteria and archaea) and eukaryotes.
Keywords: stress protection, cross effect, RF peptide reactivating factor, bacteria, archaea, yeasts, HeLa cells