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Photonuclear Alchemy: Obtaining Medical Isotopes of Gold from Mercury Irradiated on Electron Acceleratorsстатья
- Авторы: Kazakov Andrey G., Babenya Julia S., Ekatova Taisya Y., Belyshev Sergey S., Khankin Vadim V., Albaghdadi Omar, Kuznetsov Alexander A., Dovhyi Illarion I., Bezhin Nikolay A., Tananaev Ivan G.
- Журнал: Molecules
- Том: 27
- Номер: 17
- Год издания: 2022
- Издательство: MDPI
- Местоположение издательства: Basel, Switzerland
- Номер статьи: 5532
- DOI: 10.3390/molecules27175532
- Аннотация: In our work, the photonuclear production of 198,199Au isotopes for nuclear medicine purposes was studied, and a method for their recovery from irradiated mercury was developed. The yields of the corresponding nuclear reactions were determined, and a comparison of various methods of obtaining gold radioisotopes was provided. New sorbents based on benzo-15-crown-5, which selectively binds gold, were studied, and the optimal conditions for Au recovery with a high degree of purification from mercury were found. It was established that, for the fast and quantitative recovery of Au isotopes, it was necessary to add at least 0.1 mg of the carrier. As a result, the developed method can be regularly used to obtain 198,199Au for the research of radiopharmaceuticals based on them.
- Добавил в систему: Бежин Николай Алексеевич