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Synthesis of new N-(diphosphonomethyl)-containing peptides on the base of tris(trimethylsilyl) phosphiteстатья
- Авторы: Prishchenko A.A., Alekseyev R.S., Novikova O.P., Livantsov M.V., Livantsova L.I., Bararnin S.V.
- Журнал: Russian Chemical Bulletin
- Том: 71
- Номер: 9
- Год издания: 2022
- Издательство: Springer Nature
- Местоположение издательства: Switzerland
- Первая страница: 1976
- Последняя страница: 1980
- DOI: 10.1007/s11172-022-3616-x
- Аннотация: New functionalized N-(diphosphonomethyl)-containing peptides were synthesized in high yields by the reaction of tris(trimethylsilyl) phosphite with the appropriate N-formyl-peptides under mild conditions in the presence of an ef ective catalyst, trimethylsilyl trifl ate. A catalytic scheme for the formation of the products was proposed. The resulting compounds are of interest as promising biologically active substances and ef ective ligands.
- Добавил в систему: Прищенко Андрей Анатольевич