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Central vein sign for differential diagnosis of demyelinating diseases of CNSстатья
- Авторы: Belov S.E., Gubsky I.L., Lelyuk V.G., Boyko A.N.
- Журнал: Медицина экстремальных ситуаций
- Номер: 2021(3)
- Год издания: 2021
- Издательство: ФГБУ ФЦИТЭП ФМБА России
- Местоположение издательства: Москва
- Первая страница: 131
- Последняя страница: 136
- DOI: 10.47183/mes.2021.021
- Аннотация: The search for highly sensitive and highly specific biomarkers of MS, including neuroimaging biomarkers, continues. One of such biomarkers is the central veinsign detectable on SW and T2-weighted MR images. The sensitivity and specificity of methods used for central vein sign detection vary. This article describes twoclinical cases of patients with similar neurological symptoms which required making differential diagnosis between multiple sclerosis and secondary demyelinationin the presence of a systemic disorder (systemic lupus erythematosus). In addition to routine MR sequences, we used SWI generated by a 3T scanner. The lesionswith the central vein sign were counted; the proportion of perivenular lesions was determined. In the multiple sclerosis case, all the lesions were perivenular; theproportion of lesions with the central vein sign in the patient with secondary demyelination in the presence of systemic lupus erythematosus was 16.7%. The useof SW images improved the informative value of the analysis.
- Добавил в систему: Лелюк Владимир Геннадьевич