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Numerical simulations of heating patterns and tissue temperature response due to high-intensity focused ultrasoundстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
- Авторы: Curra F.P., Mourad P.D., Khokhlova V.A., Cleveland R.O., Crum L.A.
- Журнал: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
- Том: 47
- Номер: 4
- Год издания: 2000
- Издательство: Institute of Electrical and Electronics Engineers
- Местоположение издательства: Piscataway, NJ, United States
- Первая страница: 1077
- Последняя страница: 1089
- DOI: 10.1109/58.852092
- Аннотация: The results of this paper show-for an existing high intensity focused ultrasound (HIFU) transducer-the importance of nonlinear effects on the space/time properties of wave propagation and heat generation in perfused liver models when a blood vessel also might be present. These simulations are based on the nonlinear parabolic equation for sound propagation and the bio-heat equation for temperature generation. The use of high initial pressure in HIFU transducers in combination with the physical characteristics of biological tissue induces shock formation during the propagation of a therapeutic ultrasound wave. The induced shock directly affects the rate at which heat is absorbed by tissue at the focus without significant influence on the magnitude and spatial distribution of the energy being delivered. When shocks form close to the focus, nonlinear enhancement of heating is confined in a small region around the focus and generates a higher localized thermal impact on the tissue than that predicted by linear theory. The presence of a blood vessel changes the spatial distribution of both the heating rate and temperature.
- Добавил в систему: Хохлова Вера Александровна