|
ИСТИНА |
Войти в систему Регистрация |
ФНКЦ РР |
||
Usage of transcranial magnetic stimulation in the complex treatment of patients with difficult to treat depressive disorders in Parkinson's diseaseтезисы доклада Тезисы
- Авторы: Prosvetov A.O., Tsygankov B.D., Rangus S.R.
- Сборник: ŠESTI HRVATSKO – RUSKI PSIHIJATRIJSKI KONGRES s međunarodnim sudjelovanjem: Zbornik sažetaka
- Серия: 1
- Том: 1
- Тезисы
- Год издания: 2021
- Первая страница: 78
- Последняя страница: 78
- Номер статьи: 64
- Аннотация: According to the WHO, the prevalence of Parkinson's disease is 30.0-139.9 people per 100,000 population. The number of patients with Parkinson's disease in Russia is about 210,000. (Milyukhina I.V. 2019.) Mental disorders are typical for patients with Parkinson's disease. (Torgan T.I., Baidina T.V. 2012). Depressive disorder is one of the most common mental disorders, affecting an average of 40% of patients with Parkinson's disease. (Barulin A.E., Kurushina O.V., Chernovolenko E.P., 2016). In this context, the aggravation of depression in patients with Parkinson's disease appears to be an additional serious problem, and the need to treat depressive conditions in such patients is an essential part of the therapy for Parkinson's disease. Antidepressants of the selective serotonin reuptake inhibitor class, such as fluoxetine, sertraline, fluvoxamine, citalopram, etc., are the first-line therapy for depression in such patients, but antidepressant therapy is ineffective in about half of the patients. (Barone P., Antonini A., Colosimo C., et.al., 2009). Currently, for depression treatment use transcranial magnetic stimulation which is based on a series of short-term magnetic pulses of high frequency, that induce an electric impulse in specific areas of the cerebral cortex. (Belova A.N., Baldova S.N. 2015). Transcranial magnetic stimulation using a specific treatment protocol - high-frequency stimulation of the left prefrontal region - has been used for the treatment of depressive disorder in many countries, including Russia, since 2012. (Order of the Ministry of Health of the Russian Federation N 1705н 2012).However, transcranial magnetic stimulation as a treatment for depression in Parkinson's disease is poorly explored in current clinical studies. Currently, the use of transcranial magnetic stimulation as a treatment for depression in Parkinson's disease is being actively studied in many countries (Pal E, Nagy F, Aschermann Z, et al. “The impact of left prefrontal repetitive transcranial magnetic stimulation on depression in Parkinson's disease: a randomized , double-blind, placebo-controlled study ”, 2010), (Brys M, Fox MD, Agarwal S, et al.“ Multifocal repetitive TMS for motor and mood symptoms of Parkinson disease ”, 2016) and others. On the clinical base of the Department of Psychiatry, Narcology and Psychotherapy of the Moscow University of Medicine and Dentistry named after Evdokimov (head of the department - professor Tsygankov B.D.) - Scientific and Practical Psychoneurological Center named after Z.P. Solov'yev (director - professor A.B. Gecht) - since 2020, transcranial magnetic stimulation has been used in the complex treatment of depressive disorder in patients with Parkinson's disease.
- Добавил в систему: Просветов Андрей Олегович