The role of laser power and pullback velocity in the endovenous laser ablation efficacy: an experimental study Lasers Med Sciстатья
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Дата последнего поиска статьи во внешних источниках: 8 августа 2017 г.
Аннотация:Endovenous laser ablation is an effective and minimally
invasive alternative to surgical removal of incompetent
veins. However, many controversies concerning optimal laser
parameters usage in this procedure still remain. The purpose
of this experimental study was to assess the adequate parameters
required for vein wall destruction and to evaluate the role
of fiber pullback velocity on vessel wall degradation. Varicose
vein segments were treated with 1470-nm diode laser 3 to
9.5Win power. The fiber moved through the vein at a velocity
of 0.7 or 1.5 mm/s; the applied linear endovenous energy
density (LEED) was 40–95 J/cm. The temperature of the vein
surface in the course of laser irradiation was controlled by IR
thermography. The intact collagen in treated vein specimens
was studied by differential scanning calorimetry. The increase
in the surface temperature with applied energy was found to
be about three times slower for the pullback velocity of
0.7 mm/s than that of 1.5 mm/s. The collagen in the tissue
was totally denatured in the case of the surface temperature of
about 91 °C. The critical values of LEED ensured complete
degradation of vein wall were of 53 and 71.5 J/cm for velocities
of 1.5 and 0.7mm/s, respectively. Our experimental study
supports the conception that it is laser power and pullback
velocity rather than LEED value that determine the
temperature as well the collagen framework degradation and
therefore the thermal response of procedure.