Dynamic kinetic resolution of an azlactone catalyzed by octahedral chiral-at-metal Co(III) complexes under phase-transfer alcoholysisстатьяИсследовательская статья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 17 апреля 2024 г.
Аннотация:A family of well-defined octahedral cationic chiral-at-cobalt(III) catalysts based on (R,R)-1,2-cyclohexanediamine and (R,R)-1,2-diphenylethylenediamine was examined in the dynamic kinetic resolution of an azlactone derived from N-benzoyl tert-leucine. The reactions catalyzed by 10 mol% of Co(III) complexes in the presence of 1M solution of aqueous NaOH under phase-transfer alcoholysis afforded the corresponding benzyl ester of tert-leucine with up to 76% yield and up to 66% enantioselectivity (ee).