7Be and 22 Na radionuclides for a new therapy for cancer

Авторы: Kukulin Vladimir I., Bibikov Anton V., Tkalya Eugene V., Ceccarelli Matteo, Bodrenko Igor V.
Журнал: Biomolecular concepts
Том: 14
Номер: 1
Год издания: 2023
Издательство: Walter de Gruyter
Местоположение издательства: Berlin, Germany
Первая страница: 20220028
DOI: 10.1515/bmc-2022-0028
Аннотация: 10B isotopes have been almost exclusively used in the neutron-capture radiation therapy (NCT) of cancer for decades. We have identified two other nuclides suitable for radiotherapy, which have ca. ten times larger cross section of absorption for neutrons and emit heavy charged particles. This would provide several key advantages for potential NCT, such as the possibility to use a lower nuclide concentration in the target tissues or a lower neutron irradiation flux. By detecting the characteristic γ radiation from the spontaneous decay of the radionuclides, one can image their biodistribution. These advantages could open up new possibilities for NCT applications as a safer and more efficient cancer therapy.
Добавил в систему: Бибиков Антон Валентинович

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