A Raman Spectroscopic Study of the Conformation of Flavin Adenine Dinucleotide, a CoEnzyme of D-Amino Acid Oxidase

Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 29 января 2024 г.

Авторы: Bochkova J., Liu W., Brazhe N.A., Zhgun A.A., Maksimov G.V.
Журнал: Biophysics
Том: 68
Номер: 5
Год издания: 2023
Издательство: Maik Nauka/Interperiodica Publishing
Местоположение издательства: Russian Federation
Первая страница: 721
Последняя страница: 726
DOI: 10.1134/S0006350923050068
Аннотация: The spectra of surface-enhanced Raman scattering of D-amino acid oxidase from pig kidney were recorded and analyzed using silver nanoparticles; characteristic spectral parameters of changes in the confor- mation of the flavinadenine dinucleotide cofactor during activation of the enzyme by D-amino acids were revealed. It was found that the time during which changes in the conformation of the f lavinadenine dinucle- otide were recorded depended on the substrate specificity of the enzyme: in the presence of D-alanine, this took several seconds, and in the presence of D-serine, minutes.
Добавил в систему: Максимов Георгий Владимирович

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