Evaluation of the effectiveness of moisturizing toothpaste in patients with medical-induced dry mouth (pilot study)статья
Статья опубликована в журнале из списка RSCI Web of Science
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Статья опубликована в журнале из перечня ВАК
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 15 мая 2024 г.
Аннотация:The aim of the pilot study was to evaluate the effectiveness of the use of moisturizing toothpaste in patients with drug-induced dry mouth during therapy of the underlying disease. Materials and methods. According to the inclusion criteria, 80 people took part in the study, of whom 40 had dry mouth during treatment of the underlying disease and 40 people were healthy volunteers with episodic dry mouth. The effectiveness of oral hygiene was assessed using the PHP index, as well as the quality of life was assessed using the OHIP-14 questionnaire. All patients underwent professional oral hygiene using air-abrasive technology with a glycine-based powder with a particle size of 65 μm. The experimental group was prescribed for home oral hygiene using a moisturizing toothpaste with sodium PCA, betaine, mallow, xylitol. Results. Initially, an unsatisfactory level was determined both in the experimental group (2.1±0.3) and in the control group (1.8±0.1). On the 15th day of the study, the improvement in indicators was determined by 62% in the experimental group (1.3±0.2) and by 67% in the control group (1.2±0.1). A month later, in the experimental group, the index was 0.7±0.1, which is 54% in comparison with the intermediate situation, and in the control group, 0.6±0.2, accounting for 50% of the increase in efficiency. Assessment of the quality of life showed an improvement from 44.3±0.4 to 25.2±0.3 (p<0.05) and in the control group from 16.7±0.1 up to 14.1±0.2 (p<0.05). Conclusions. The clinical efficacy of the use of a moisturizing toothpaste in patients with drug-induced dry mouth during treatment of the underlying disease has been shown.