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The American lobster genome reveals insights on longevity, neural, and immune adaptationsстатья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или Scopus- Авторы: Polinski Jennifer M., Zimin Aleksey V., Clark K.Fraser, Kohn Andrea B., Sadowski Norah, Timp Winston, Ptitsyn Andrey, Khanna Prarthana, Romanova Daria Y., Williams Peter, Greenwood Spencer J., Moroz Leonid L., Walt David R., Bodnar Andrea G.
- Журнал: Science Advances
- Том: 7
- Номер: 26
- Год издания: 2021
- DOI: 10.1126/sciadv.abe8290
- Аннотация: The American lobster, Homarus americanus, is integral to marine ecosystems and supports an important commercial fishery. This iconic species also serves as a valuable model for deciphering neural networks controlling rhythmic motor patterns and olfaction. Here, we report a high-quality draft assembly of the H. americanus genome with 25,284 predicted gene models. Analysis of the neural gene complement revealed extraordinary development of the chemosensory machinery, including a profound diversification of ligand-gated ion channels and secretory molecules. The discovery of a novel class of chimeric receptors coupling pattern recognition and neurotransmitter binding suggests a deep integration between the neural and immune systems. A robust repertoire of genes involved in innate immunity, genome stability, cell survival, chemical defense, and cuticle formation represents a diversity of defense mechanisms essential to thrive in the benthic marine environment. Together, these unique evolutionary adaptations contribute to the longevity and ecological success of this long-lived benthic predator.
- Добавил в систему: Романова Дарья Юрьевна