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A.A Hexaamineruthenium as an electron donor to mitochondrial cytochrome oxidase:membrane potential generation in the absence of cytochrome cстатья
Информация о цитировании статьи получена из
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Web of Science
Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
- Авторы: Tzofina L.M., Liberman E.A., Vygodina T.V., Konstantinov
- Журнал: Biochemistry international
- Том: 12
- Номер: 1
- Год издания: 1986
- Издательство: Published for the International Union of Biochemistry by Academic Press
- Местоположение издательства: Sydney ; New York, Australia
- Первая страница: 103
- Последняя страница: 110
- DOI: PMID:3004496
- Аннотация: Cytochrome c oxidase can generate membrane potential in the absence of cytochrome c (e.g., in cytochrome c-deficient mitochondria or in proteoliposomes) with hexaammineruthenium as an artificial electron donor. Of several other redox mediators tested, phenazine methosulfate was found to be an efficient artificial substrate for membrane energization by cytochrome oxidase, whereas TMPD, DAD, DCPIP or ferrocyanide are virtually ineffective. The ability of Ru(NH3)6(2+) and phenazine methosulfate to support the generation of delta psi by cytochrome c-oxidase correlates with their effectiveness as electron donors to cytochrome a in the cyanide-inhibited membrane-bound enzyme.
- Добавил в систему: Выгодина Татьяна Владимировна