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Neuroprotective effect of mesenchymal and neural stem and progenitor cells on sensorimotor recovery after brain injuryстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 12 июля 2019 г.
- Авторы: Poltavtseva R.A., Silachev D.N., Pavlovich S.V., Kesova M.I., Yarygin K.N., Lupatov A.Y., Van’ko L.V., Shuvalova M.P., Sukhikh G.T.
- Журнал: Bulletin of Experimental Biology and Medicine
- Том: 153
- Номер: 4
- Год издания: 2012
- Издательство: Springer Nature
- Местоположение издательства: Switzerland
- Первая страница: 586
- Последняя страница: 590
- Аннотация: We studied the effect of systemic administration of multipotent stem cells on impaired neurological status in rats with brain injury. It was found that transplantation of multipotent mesenchymal stromal cells of the bone marrow or human neural stem and progenitor cells to rats with local brain injury promoted recovery of the brain control over locomotor function and proprioceptive sensitivity of forelegs. The dynamics of neurological recovery was similar after transplantation of fetal neural stem and progenitor cells and multipotent mesenchymal stromal cells. Transplantation of cell cultures improved survival of experimental animals. It should be noted that administration of neural stem and progenitor cells prevented animal death not only in the acute traumatic period, but also in delayed periods.
- Добавил в систему: Силачёв Денис Николаевич